Benzene, 1-fluoro-2-isocyanato-4-(trifluoromethyl)- (9CI)
2-Fluoro-5-(trifluoromethyl)phenyl isocyanate
CAS: 69922-27-6
Molecular Formula: C8H3F4NO
Benzene, 1-fluoro-2-isocyanato-4-(trifluoromethyl)- (9CI) - Names and Identifiers
Benzene, 1-fluoro-2-isocyanato-4-(trifluoromethyl)- (9CI) - Physico-chemical Properties
| Molecular Formula | C8H3F4NO |
| Molar Mass | 205.11 |
| Density | 1.418g/mLat 25°C(lit.) |
| Boling Point | 53°C2.5mm Hg(lit.) |
| Flash Point | 159°F |
| Vapor Presure | 1.65mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear colorless |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.455(lit.) |
Benzene, 1-fluoro-2-isocyanato-4-(trifluoromethyl)- (9CI) - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 2922 8/PG 3 |
| WGK Germany | 3 |
| HS Code | 29291090 |
| Hazard Note | Corrosive/Lacrymatory |
| Hazard Class | 6.1 |
| Packing Group | II |
Benzene, 1-fluoro-2-isocyanato-4-(trifluoromethyl)- (9CI) - Introduction
2-Fluoro-5-(trifluoromethyl)phenyl isocyanate is a chemical substance that has the following properties:
Appearance: 2-Fluoro-5-(trifluoromethyl)phenyl isocyanate is a colorless to pale yellow liquid.
Molecular formula: C8H4F4N2O
Molecular weight: 228.12g/mol
Boiling point: approximately 100-107°C
Density: 1.42g/cm³
Flash Point: 95°C
2-Fluoro-5-(trifluoromethyl)phenyl isocyanate is mainly used in organic synthesis, especially in the manufacture of pesticides, drugs and specialty chemicals. It can be used as a reagent for the synthesis of carbamate compounds. It is a useful intermediate for the synthesis of biologically active organic molecules.
The preparation method can be achieved by reacting p-difluorophenol with trifluoroacetate under alkaline conditions. The difluorophenol is first reacted with the trifluoroacetate to form the corresponding fluoride, which is then esterified with an isocyanate under basic conditions.
During the operation, you need to pay attention to the safety information of the 2-Fluoro-5-(trifluoromethyl)phenyl isocyanate. It is an organic compound, so it needs to be handled in the laboratory, following the relevant safe operating procedures. It is an irritating and highly toxic substance. Direct contact with skin and eyes should be avoided. Appropriate personal protective equipment such as gloves, protective glasses and laboratory coats should be worn. In addition, it should be operated under ventilated conditions to prevent its vapor accumulation. If accidentally ingested or inhaled, should promptly seek medical attention. In the process of storage and handling, it should be placed in isolation from other chemicals to avoid fire and high temperature.
Appearance: 2-Fluoro-5-(trifluoromethyl)phenyl isocyanate is a colorless to pale yellow liquid.
Molecular formula: C8H4F4N2O
Molecular weight: 228.12g/mol
Boiling point: approximately 100-107°C
Density: 1.42g/cm³
Flash Point: 95°C
2-Fluoro-5-(trifluoromethyl)phenyl isocyanate is mainly used in organic synthesis, especially in the manufacture of pesticides, drugs and specialty chemicals. It can be used as a reagent for the synthesis of carbamate compounds. It is a useful intermediate for the synthesis of biologically active organic molecules.
The preparation method can be achieved by reacting p-difluorophenol with trifluoroacetate under alkaline conditions. The difluorophenol is first reacted with the trifluoroacetate to form the corresponding fluoride, which is then esterified with an isocyanate under basic conditions.
During the operation, you need to pay attention to the safety information of the 2-Fluoro-5-(trifluoromethyl)phenyl isocyanate. It is an organic compound, so it needs to be handled in the laboratory, following the relevant safe operating procedures. It is an irritating and highly toxic substance. Direct contact with skin and eyes should be avoided. Appropriate personal protective equipment such as gloves, protective glasses and laboratory coats should be worn. In addition, it should be operated under ventilated conditions to prevent its vapor accumulation. If accidentally ingested or inhaled, should promptly seek medical attention. In the process of storage and handling, it should be placed in isolation from other chemicals to avoid fire and high temperature.
Last Update：2024-04-09 20:52:54
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Product Name: 2-Fluoro-5-(Trifluoromethyl)Phenyl Isocyanate Visit Supplier Webpage Request for quotation
CAS: 69922-27-6
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 69922-27-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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